Diethylpropion and mazindol: An end to the discussion?

Systematic review and meta-analysis of the efficacy and safety of amfepramone and mazindol as a monotherapy for the treatment of obese or overweight patients

[This corrects the article doi: 10.6061/clinics/2017(05)10].

Obesity in adults.

INTRODUCTION About one third of the US population and one quarter of the UK population are obese, with increased risks of hypertension, dyslipidaemia, diabetes, cardiovascular disease, osteoarthritis, and some cancers. Fewer than 10% of overweight or obese adults aged 40 to 49 years revert to a normal body weight after 4 years. Nearly 5 million US adults used prescription weight-loss medication...

Voltammetric Behavior of Amfepramone (Diethylpropion) at the Hanging Mercury Drop Electrode and its Analytical Determination in Pharmaceutical Formulations

Este trabalho descreve um estudo sistemático do comportamento voltamétrico da anfepramona no eletrodo de mercúrio de gota pendente (HMDE) por voltametria cíclica (CV) e voltametria de corrente alternada (AC). Os estudos mostraram o comportamento adsortivo da anfepramona no HMDE e foram realizados em soluções de H 2 SO 4 0,1 mol L (pH 1.0) e tampão de Ringer (pH 11,0) como eletrólito suporte. A ...

Efficacy of Long-term Obesity’s Treatment with Diethylpropion

Objective: To evaluate the efficacy and safety of long-term continuing treatment (24 months) of Diethylpropion (DEP) for weight loss in obese subjects. Research Methods and Procedures: A large, multicenter, randomized, placebocontrolled, dose-ranging trial in 3688 subjects demonstrated that DEP plus individualized nutritional intervention causes a dose-dependent decrease in body weight. The lon...

[excitatory Poisonings with Diethylpropion (dobesin), Especially in Children].